![]() ![]() This test was more simple, and rapid for the diagnosis of HS than ordinary osmotic fragility test. Since ΔOD/min showed a significant correlation with the osmotic fragility test, ΔOD/min would be able to use one of the screening tests for the HS. ![]() At the diagnosis of HS, the AGLT10 and ΔOD/min offered more accurate rather than the AGLT50. This modified AGLT was applied to the patients with HS, 56 patients with various hematological disorders, and 10 normal subjects. the optical density to fall to 10% of the initial value) and ΔOD/min (decrement of a variable optical density for one minute after an adding glycerol reagent). We have devised a new analyzing method, AGLT10 (time required for. This test became occasionally false positive when the results were analyzed by AGLT50 (time required for the optical density to fall to half of the initial value after the glycerol reagent added). The acidified glycerol lysis test (AGLT) has been recently used for the diagnosis of hereditary spherocytosis (HS) as a screening test. ![]()
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